Enhanced production of Chikungunya virus-like particles using a high-pH adapted spodoptera frugiperda insect cell line.

Chikungunya virus-like particles (VLPs) have potential to be used as a prophylactic vaccine based on testing in multiple animal models and are currently being evaluated for human use in a Phase I clinical trial. The current method for producing these enveloped alphavirus VLPs by transient gene expre...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: James M Wagner, J David Pajerowski, Christopher L Daniels, Patrick M McHugh, Jessica A Flynn, John W Balliet, Danilo R Casimiro, Shyamsundar Subramanian
स्वरूप: लेख
भाषा:English
प्रकाशित: Public Library of Science (PLoS) 2014-01-01
श्रृंखला:PLoS ONE
ऑनलाइन पहुंच:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094401&type=printable