Enrichment of homologs in insignificant BLAST hits by co-complex network alignment

<p>Abstract</p> <p>Background</p> <p>Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stringent score cutoff is applied to distinguish putative homologs fro...

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Bibliographic Details
Main Authors: Boekhorst Jos, Botelho Sandra MC, Fokkens Like, Snel Berend
Format: Article
Language:English
Published: BMC 2010-02-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/86