Twin Promotes the Maintenance and Differentiation of Germline Stem Cell Lineage through Modulation of Multiple Pathways

The central question in stem cell regulation is how the balance between self-renewal and differentiation is controlled at the molecular level. This study uses germline stem cells (GSCs) in the Drosophila ovary to demonstrate that the Drosophila CCR4 homolog Twin is required intrinsically to promote...

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Bibliographic Details
Main Authors: Ziwen Fu, Cuiyun Geng, Hui Wang, Zhihao Yang, Changjiang Weng, Hua Li, Lamei Deng, Luping Liu, Nan Liu, Jianquan Ni, Ting Xie
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715011717