B-cell activating factor and IL-21 levels predict treatment response in autoimmune hepatitis

B-cell activating factor and IL-21 levels predict treatment response in autoimmune hepatitis

Background & Aims: Increased serum IgG and autoantibodies suggest involvement of B cells in autoimmune hepatitis (AIH). The aim of this study was to assess levels of B cell activating factor of the tumour necrosis family (BAFF), IL-21, and circulating B cell populations in AIH and correlate...

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Bibliographic Details
Main Authors: Maaike Biewenga, Sebastiaan Heidt, Manon Vergunst, Camiel M.J. Marijnissen, Rob A. de Man, Annemiek A. van der Eijk, Adriaan J. van der Meer, Leendert A. Trouw, Bart van Hoek
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:JHEP Reports
Subjects:
Autoimmune hepatitis
BAFF
IL-21
B-cell immunity
Biochemical remission
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555922000325

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http://www.sciencedirect.com/science/article/pii/S2589555922000325

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