Polo-like kinase 1 inhibition in NSCLC: mechanism of action and emerging predictive biomarkers

Polo-like kinase 1 inhibition in NSCLC: mechanism of action and emerging predictive biomarkers

Jan A Stratmann, Martin SebastianDepartment of Internal Medicine II, University Clinic of Frankfurt, 60596 Frankfurt, GermanyAbstract: Non-small cell lung cancer (NSCLC) is the leading cause of cancer death worldwide. Due to often unspecific disease symptoms, locally advanced or metastatic disease i...

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Bibliographic Details
Main Authors: Stratmann JA, Sebastian M
Format: Article
Language:English
Published: Dove Medical Press 2019-07-01
Series:Lung Cancer: Targets and Therapy
Subjects:
non-small cell lung cancer
polo-like kinase
targeted therapy
therapy resistance
Online Access:https://www.dovepress.com/polo-like-kinase-1-inhibition-in-nsclc-mechanism-of-action-and-emergin-peer-reviewed-article-LCTT

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https://www.dovepress.com/polo-like-kinase-1-inhibition-in-nsclc-mechanism-of-action-and-emergin-peer-reviewed-article-LCTT

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