Optical microscopy reveals the dynamic nature of B. pseudomallei morphology during β-lactam antimicrobial susceptibility testing

Optical microscopy reveals the dynamic nature of B. pseudomallei morphology during β-lactam antimicrobial susceptibility testing

Abstract Background In Gram-negative species, β-lactam antibiotics target penicillin binding proteins (PBPs) resulting in morphological alterations of bacterial cells. Observations of antibiotic-induced cell morphology changes can rapidly and accurately differentiate drug susceptible from resistant...

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Bibliographic Details
Main Authors: Heather P. McLaughlin, Julia Bugrysheva, David Sue
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Microbiology
Subjects:
Cell morphology
B. pseudomallei
β-lactam antibiotics
Online Access:http://link.springer.com/article/10.1186/s12866-020-01865-w

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http://link.springer.com/article/10.1186/s12866-020-01865-w

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