Evaluation of Cytotoxicity Effects of Chalcone Epoxide Analogues as a Selective COX-II Inhibitor in the Human Liver Carcinoma Cell Line

Objectives: Study of the mechanisms involved in cancer progression suggests that cyclooxygenase enzymes play an important role in the induction of inflammation, tumor formation, and metastasis of cancer cells. Thus, cyclooxygenase enzymes could be considered for cancer chemotherapy. Among these enzy...

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Bibliographic Details
Main Authors: Pouran Makhdoumi, Afshin Zarghi, Bahram Daraei, Gholamreza Karimi
Format: Article
Language:English
Published: Korean Pharmacopuncture Institute 2017-09-01
Series:Journal of Pharmacopuncture
Subjects:
Online Access:https://doi.org/10.3831/KPI.2017.20.024