Influence of Streptococcus pneumoniae Within-Strain Population Diversity on Virulence and Pathogenesis
ABSTRACT The short generation time of many bacterial pathogens allows the accumulation of de novo mutations during routine culture procedures used for the preparation and propagation of bacterial stocks. Taking the major human pathogen Streptococcus pneumoniae as an example, we sought to determine t...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2023-02-01
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Series: | Microbiology Spectrum |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/spectrum.03103-22 |