Influence of Streptococcus pneumoniae Within-Strain Population Diversity on Virulence and Pathogenesis

ABSTRACT The short generation time of many bacterial pathogens allows the accumulation of de novo mutations during routine culture procedures used for the preparation and propagation of bacterial stocks. Taking the major human pathogen Streptococcus pneumoniae as an example, we sought to determine t...

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Bibliographic Details
Main Authors: Laura C. Jacques, Angharad E. Green, Thomas E. Barton, Murielle Baltazar, Julia Aleksandrowicz, Rong Xu, Erwan Trochu, Aras Kadioglu, Daniel R. Neill
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03103-22