Current advances and challenges in Managing Hereditary Diffuse Gastric Cancer (HDGC): a narrative review

Current advances and challenges in Managing Hereditary Diffuse Gastric Cancer (HDGC): a narrative review

Abstract More than 25 years ago, CDH1 pathogenic variants (PVs) were identified as the primary cause of hereditary diffuse gastric cancer (HDGC), an inherited cancer syndrome that increases the lifetime risk of developing diffuse gastric cancer (DGC) and lobular breast cancer (LBC). Since DGC is ass...

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Bibliographic Details
Main Authors: L. van der Sluis, J.M. van Dieren, R.S. van der Post, T.M. Bisseling
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
HDGC
CDH1
CTNNA1
Diffuse gastric cancer
Endoscopic surveillance
Online Access:https://doi.org/10.1186/s13053-024-00293-5

Internet

https://doi.org/10.1186/s13053-024-00293-5

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