Association between acetaminophen metabolites and CYP2E1 DNA methylation level in neonate cord blood in the Boston Birth Cohort

Abstract Background Acetaminophen is a commonly used medication by pregnant women and is known to cross the placenta. However, little is known about the biological mechanisms that regulate acetaminophen in the developing offspring. Cytochrome 2E1 (CYP2E1) is the primary enzyme responsible for the co...

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Bibliographic Details
Main Authors: Yijun Li, Xiumei Hong, Liming Liang, Xiaobin Wang, Christine Ladd-Acosta
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Clinical Epigenetics
Subjects:
Online Access:https://doi.org/10.1186/s13148-023-01551-4