Assembling the perfect bacterial genome using Oxford Nanopore and Illumina sequencing.

A perfect bacterial genome assembly is one where the assembled sequence is an exact match for the organism's genome-each replicon sequence is complete and contains no errors. While this has been difficult to achieve in the past, improvements in long-read sequencing, assemblers, and polishers ha...

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Bibliographic Details
Main Authors: Ryan R Wick, Louise M Judd, Kathryn E Holt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010905