Argonaute 2 restored erectile function and corpus cavernosum mitochondrial function by reducing apoptosis in a mouse model of cavernous nerve injury

Argonaute 2 restored erectile function and corpus cavernosum mitochondrial function by reducing apoptosis in a mouse model of cavernous nerve injury

Purpose: To determine whether the overexpression of the Argonaute RNA-induced silencing complex catalytic component 2 (Ago2) improves erectile function in mice after cavernous nerve injury (CNI). Materials and Methods: Lentiviruses containing Ago2 open reading frame (ORF) mouse clone (Ago2 O/E) wer...

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Bibliographic Details
Main Authors: Yan Huang, Guo Nan Yin, Fang-Yuan Liu, Fitri Rahma Fridayana, Lashkari Niloofar, Minh Nhat Vo, Ji-Kan Ryu
Format: Article
Language:English
Published: Korean Urological Association 2024-07-01
Series:Investigative and Clinical Urology
Subjects:
apoptosis
argonaute proteins
mitochondria dysfunction
nerve regeneration
reactive oxygen species
Online Access:https://icurology.org/pdf/10.4111/icu.20240077

Internet

https://icurology.org/pdf/10.4111/icu.20240077

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