Insulin resistance in Alzheimer's disease

Insulin is a key hormone regulating metabolism. Insulin binding to cell surface insulin receptors engages many signaling intermediates operating in parallel and in series to control glucose, energy, and lipids while also regulating mitogenesis and development. Perturbations in the function of any of...

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Bibliographic Details
Main Authors: Kelly T. Dineley, Jordan B. Jahrling, Larry Denner
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002642