The Effects of a Novel Non-catechol Dopamine Partial Agonist on Working Memory in the Aged Rhesus Monkey

The Effects of a Novel Non-catechol Dopamine Partial Agonist on Working Memory in the Aged Rhesus Monkey

Aged-related declines in cognition, especially working memory and executive function, begin in middle-age and these abilities are known to be mediated by the prefrontal cortex (PFC) and more specifically the dopamine (DA) system within the PFC. In both humans and monkeys, there is significant eviden...

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Bibliographic Details
Main Authors: Tara L. Moore, Damon A. Young, Ronald J. Killiany, Kari R. Fonseca, Dmitri Volfson, David L. Gray, Rita Balice-Gordon, Rouba Kozak
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
dopamine
aging
prefrontal cortex
rhesus monkey
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.757850/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2021.757850/full

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