MiR-199b-5p Suppresses Tumor Angiogenesis Mediated by Vascular Endothelial Cells in Breast Cancer by Targeting ALK1

MiR-199b-5p Suppresses Tumor Angiogenesis Mediated by Vascular Endothelial Cells in Breast Cancer by Targeting ALK1

Angiogenesis is a crucial event during cancer progression that regulates tumor growth and metastasis. Activin receptor-like kinase 1 (ALK1), predominantly expressed in endothelial cells, plays a key role in the organization of neo-angiogenic vessels. Therapeutic targeting of ALK1 has been proposed a...

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Bibliographic Details
Main Authors: Xiao Lin, Wuxia Qiu, Yunyun Xiao, Jianhua Ma, Fang Xu, Kewen Zhang, Yongguang Gao, Qiang Chen, Yu Li, Hui Li, Airong Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Genetics
Subjects:
angiogenesis
miR-199b-5p
ALK1
HUVECs
tumor growth
breast cancer
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01397/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.01397/full

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