Association of CDH1 Germline Variants and Colon Polyp Phenotypes in Patients With Hereditary Diffuse Gastric Cancer

Association of CDH1 Germline Variants and Colon Polyp Phenotypes in Patients With Hereditary Diffuse Gastric Cancer

Background and Aims: Germline CDH1 variants resulting in E-cadherin loss of function result in an increased risk of diffuse type gastric cancer and lobular type breast cancer. However, the risk of developing other epithelial neoplasms, specifically colorectal cancer, is unknown. Methods: Patients en...

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Bibliographic Details
Main Authors: Monica Passi, Lauren A. Gamble, Sarah G. Samaranayake, Samuel A. Schueler, Bryan F. Curtin, Grace-Ann Fasaye, Cassidy Bowden, Sandeep Gurram, Martha Quezado, Markku Miettinen, Christopher Koh, Theo Heller, Jeremy L. Davis
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Gastro Hep Advances
Subjects:
CDH1
Hereditary diffuse gastric cancer
Colon polyps
Colorectal cancer
Cancer screening
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572322001728

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http://www.sciencedirect.com/science/article/pii/S2772572322001728

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