Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study

<p>Abstract</p> <p>Background</p> <p>Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key mechanism in this technique is to design efficient siRNAs that in...

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Bibliographic Details
Main Authors: Xue Hong, Zheng Vincent W, Xu Qian, Liu Qi, Cao Zhiwei, Yang Qiang
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/181