Integrated Microarray-Based Data Analysis of miRNA Expression Profiles: Identification of Novel Biomarkers of Cisplatin-Resistance in Testicular Germ Cell Tumours

Integrated Microarray-Based Data Analysis of miRNA Expression Profiles: Identification of Novel Biomarkers of Cisplatin-Resistance in Testicular Germ Cell Tumours

Testicular germ cell tumours (TGCTs) are the most common solid malignancy among young men, and their incidence is still increasing. Despite good curability with cisplatin (CDDP)-based chemotherapy, about 10% of TGCTs are non-responsive and show a chemoresistant phenotype. To further increase TGCT cu...

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Bibliographic Details
Main Authors: Jan Roška, João Lobo, Danica Ivovič, Lenka Wachsmannová, Thomas Mueller, Rui Henrique, Carmen Jerónimo, Miroslav Chovanec, Dana Jurkovičová
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
miRNA microarray
miRNA
cisplatin
testicular germ cell tumour
biomarker
Online Access:https://www.mdpi.com/1422-0067/24/3/2495

Internet

https://www.mdpi.com/1422-0067/24/3/2495

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