Nanosized Liposomes Containing Bile Salt: A Vesicular Nanocarrier for Enhancing Oral Bioavailability of BCS Class III Drug

PURPOSE: Liposomes have been studied as a colloidal carrier in drug delivery systems, especially for oral administration. However, their low structural integrity in the gut is still a major shortcoming. Membrane disruptive effects of physiological bile salts in the small intestine result in prematur...

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Bibliographic Details
Main Authors: Mosab Arafat, Cathrin Kirchhoefer, Momir Mikov, Muhammad Sarfraz, Raimar Löbenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-08-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/29340