Ligand Docking Methods to Recognize Allosteric Inhibitors for G-Protein-Coupled Receptors

G-protein-coupled receptors (GPCRs) are membrane proteins which play an important role in many cellular processes and are excellent drug targets. Despite the existence of several US Food and Drug Administration (FDA)-approved GPCR-targeting drugs, there is a continuing challenge of side effects owin...

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Bibliographic Details
Main Authors: K Harini, S Jayashree, Vikas Tiwari, Sneha Vishwanath, Ramanathan Sowdhamini
Format: Article
Language:English
Published: SAGE Publishing 2021-10-01
Series:Bioinformatics and Biology Insights
Online Access:https://doi.org/10.1177/11779322211037769