Second generation androgen receptor antagonists and challenges in prostate cancer treatment
Abstract Prostate cancer is a hormone-dependent malignancy, whose onset and progression are closely related to the activity of the androgen receptor (AR) signaling pathway. Due to this critical role of AR signaling in driving prostate cancer, therapy targeting the AR pathway has been the mainstay st...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-07-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-022-05084-1 |