Application of probabilistic methods to address variability and uncertainty in estimating risks for non-cancer health effects

Abstract Human health risk assessment currently uses the reference dose or reference concentration (RfD, RfC) approach to describe the level of exposure to chemical hazards without appreciable risk for non-cancer health effects in people. However, this “bright line” approach assumes that there is mi...

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Bibliographic Details
Main Authors: Greylin H. Nielsen, Wendy J. Heiger-Bernays, Jonathan I. Levy, Roberta F. White, Daniel A. Axelrad, Juleen Lam, Nicholas Chartres, Dimitri Panagopoulos Abrahamsson, Swati D. G. Rayasam, Rachel M. Shaffer, Lauren Zeise, Tracey J. Woodruff, Gary L. Ginsberg
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Environmental Health
Subjects:
Online Access:https://doi.org/10.1186/s12940-022-00918-z