Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development.

All cellular phenomena and developmental events, including inner ear development, are modulated through harmonized signaling networks. Phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a tumor suppressor, is a major signaling component involved in cross talk with key regulators of deve...

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Bibliographic Details
Main Authors: Hyung Jin Kim, Hae-Mi Woo, Jihee Ryu, Jinwoong Bok, Jin Woo Kim, Sang Back Choi, Mi-Hyun Park, Hyun-Young Park, Soo Kyung Koo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3564925?pdf=render