Green Tea Catechins Modulate Skeletal Development with Effects Dependent on Dose, Time, and Structure in a down Syndrome Mouse Model

Green Tea Catechins Modulate Skeletal Development with Effects Dependent on Dose, Time, and Structure in a down Syndrome Mouse Model

Altered skeletal development in Down syndrome (DS) results in a brachycephalic skull, flattened face, shorter mandibular ramus, shorter limbs, and reduced bone mineral density (BMD). Our previous study showed that low doses of green tea extract enriched in epigallocatechin-3-gallate (GTE-EGCG), admi...

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Bibliographic Details
Main Authors: Sergi Llambrich, Rubèn González-Colom, Jens Wouters, Jorge Roldán, Sara Salassa, Kaat Wouters, Vicky Van Bulck, James Sharpe, Zsuzsanna Callaerts-Vegh, Greetje Vande Velde, Neus Martínez-Abadías
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Nutrients
Subjects:
skeletal development
Down syndrome
EGCG
µCT
Online Access:https://www.mdpi.com/2072-6643/14/19/4167

Internet

https://www.mdpi.com/2072-6643/14/19/4167

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