Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study

Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study

Background: Genetic diversity in human leukocyte antigen (HLA) alleles across populations is a significant risk factor for drug-induced severe cutaneous adverse reactions (SCARs), e.g., carbamazepine (CBZ)- and lamotrigine (LTG)-induced Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis...

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Bibliographic Details
Main Authors: Ladan Dastgheib, Farima Rostams, Behrouz Gharesi-Fard, Ali Akbar Asadi-Pooya, Saba Namjoo, Foroozan Tahmasebi, Maryam Hadibarhaghtalab
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-01-01
Series:Iranian Journal of Medical Sciences
Subjects:
stevens-johnson syndrome
anticonvulsants
histocompatibility testing
Online Access:https://ijms.sums.ac.ir/article_48904_e9fe90af09d2e3701dac02096dc69047.pdf

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https://ijms.sums.ac.ir/article_48904_e9fe90af09d2e3701dac02096dc69047.pdf

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