Selected Thiadiazine-Thione Derivatives Attenuate Neuroinflammation in Chronic Constriction Injury Induced Neuropathy

Selected Thiadiazine-Thione Derivatives Attenuate Neuroinflammation in Chronic Constriction Injury Induced Neuropathy

Neuropathic pain refers to a lesion or disease of peripheral and/or central somatosensory neurons and is an important body response to actual or potential nerve damage. We investigated the therapeutic potential of two thiadiazine-thione [TDT] derivatives, 2-(5-propyl-6-thioxo-1, 3, 5-thiadiazinan-3-...

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Bibliographic Details
Main Authors: Sonia Qureshi, Gowhar Ali, Muhammad Idrees, Tahir Muhammad, Il-Keun Kong, Muzaffar Abbas, Muhammad Ishaq Ali Shah, Sajjad Ahmad, Robert D. E. Sewell, Sami Ullah
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
thiadiazine-thione
neuropathic pain
allodynia/hyperalgesia
astrocyte
tumor necrotic factor-alpha
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2021.728128/full

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https://www.frontiersin.org/articles/10.3389/fnmol.2021.728128/full

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