Genomic characterization of equine influenza A subtype H3N8 viruses by long read sequencing and functional analyses of the PB1-F2 virulence factor of A/equine/Paris/1/2018

Genomic characterization of equine influenza A subtype H3N8 viruses by long read sequencing and functional analyses of the PB1-F2 virulence factor of A/equine/Paris/1/2018

Abstract Equine influenza virus (EIV) remains a threat to horses, despite the availability of vaccines. Strategies to monitor the virus and prevent potential vaccine failure revolve around serological assays, RT-qPCR amplification, and sequencing the viral hemagglutinin (HA) and neuraminidase (NA) g...

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Bibliographic Details
Main Authors: Lena Kleij, Elise Bruder, Dorothée Raoux-Barbot, Nathalie Lejal, Quentin Nevers, Charlotte Deloizy, Bruno Da Costa, Loïc Legrand, Eric Barrey, Alexandre Chenal, Stéphane Pronost, Bernard Delmas, Sophie Dhorne-Pollet
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Veterinary Research
Subjects:
Nucleotide sequencing
equine influenza
equine influenza virus
H3N8
nanopore
PB1-F2
Online Access:https://doi.org/10.1186/s13567-024-01289-8

Internet

https://doi.org/10.1186/s13567-024-01289-8

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