Clinical validation of a liquid chromatography-tandem mass spectrometry method for the quantification of calcineurin and mTOR inhibitors in dried matrix on paper discs

Introduction: Advances in liquid chromatography coupled to tandem mass spectrometry (LC–MS/MS) have enabled the quantification of immunosuppressants using microsampling techniques. In this context, dried matrix on paper discs (DMPD) could be a useful alternative to conventional venipuncture. Althoug...

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Bibliographic Details
Main Authors: Ignacio Guillermo Bressán, María Isabel Giménez, Susana Francisca Llesuy
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X22000177