Histone Deacetylase Inhibitors Restore Cancer Cell Sensitivity towards T Lymphocytes Mediated Cytotoxicity in Pancreatic Cancer

Histone Deacetylase Inhibitors Restore Cancer Cell Sensitivity towards T Lymphocytes Mediated Cytotoxicity in Pancreatic Cancer

Despite medical advancements, the prognosis of pancreatic ductal adenocarcinoma (PDAC) has not improved significantly over the past 50 years. By utilising the large-scale genomic datasets available from the Australia Pancreatic Cancer Project (PACA-AU) and The Cancer Genomic Atlas Project (TCGA-PAAD...

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Bibliographic Details
Main Authors: Chin-King Looi, Li-Lian Gan, Wynne Sim, Ling-Wei Hii, Felicia Fei-Lei Chung, Chee-Onn Leong, Wei-Meng Lim, Chun-Wai Mai
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
pancreatic ductal adenocarcinoma
cytotoxic T lymphocytes resistance
histone deactylase inhibitors
Online Access:https://www.mdpi.com/2072-6694/14/15/3709

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https://www.mdpi.com/2072-6694/14/15/3709

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