Dexmedetomidine relieves ischaemia-reperfusion injury of kidney via up-regulation of sirtuin 3

Dexmedetomidine relieves ischaemia-reperfusion injury of kidney via up-regulation of sirtuin 3

Objective To study the protective effect and mechanism of dexmedetomidine (DEX) on renal ischemia-reperfusion (I/R) injury in mice. Methods The mice were divided into sham group, siRNA+sham group, renal I/R group (conventional method), DEX+I/R group (25 μg/kg DEX, intraperitoneal injection), siRNA+I...

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Bibliographic Details
Main Author: WU Yue-ling, QU Hai-xia, WANG Jun-xing
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2020-03-01
Series:Jichu yixue yu linchuang
Subjects:
acute kidney injury|dexmedetomidine|mitochondrial damage|sirtuin 3
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a190390.pdf

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http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a190390.pdf

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