Loud noise-exposure changes the firing frequency of subtypes of layer 5 pyramidal neurons and Martinotti cells in the mouse auditory cortex

Loud noise-exposure changes the firing frequency of subtypes of layer 5 pyramidal neurons and Martinotti cells in the mouse auditory cortex

IntroductionLoud noise-exposure can generate noise-induced tinnitus in both humans and animals. Imaging and in vivo studies show that noise exposure affects the auditory cortex; however, cellular mechanisms of tinnitus generation are unclear.MethodsHere we compare membrane properties of layer 5 (L5)...

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Bibliographic Details
Main Authors: Ingrid Nogueira, Thiago Z. Lima, Thawann Malfatti, Katarina E. Leao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
auditory system
electrophysiology
tinnitus mechanisms
whole-cell patch clamp
principal component analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1152497/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1152497/full

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