Cathepsin B Is Upregulated and Mediates ECM Degradation in Colon Adenocarcinoma HT29 Cells Overexpressing Snail

During tumor development and ongoing metastasis the acquisition of mesenchymal cell traits by epithelial carcinoma cells is achieved through a programmed phenotypic shift called the epithelial-to-mesenchymal transition, EMT. EMT contributes to increased cancer cell motility and invasiveness mainly t...

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Bibliographic Details
Main Authors: Jakub Kryczka, Izabela Papiewska-Pajak, M. Anna Kowalska, Joanna Boncela
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/8/3/203