Automated Synthesis of 18F-AV45 for Aβ-Amyloid Imaging and its Preliminary Clinical Application

Aβ-Amyloid positron imaging agent 18F-AV45 was synthesized automatically using TRACERlab FX2 N radiosynthesis module and the clinical imaging of 18F-AV45 was evaluated. AV105 was used as the precursor, which reacted with 18F ion at 130 ℃ for 10 minutes on the TRACERlab FX2 N, followed by acid hydrol...

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Bibliographic Details
Main Author: HUANG Zhenghai;REN Chao;ZHU Shikun;WANG Xuezhu;WU Meiqi;HUO Li
Format: Article
Language:zho
Published: Editorial Board of Journal of Isotopes 2021-08-01
Series:Journal of Isotopes
Subjects:
Online Access:http://www.tws.org.cn/CN/10.7538/tws.2021.34.04.0363