The timing of IFNβ production affects early innate responses to Listeria monocytogenes and determines the overall outcome of lethal infection.

Dendritic cells (DCs) and natural killer (NK) cells are essential components of the innate immunity and play a crucial role in the first phase of host defense against infections and tumors. Listeria monocytogenes (Lm) is an intracellular pathogen that colonizes the cytosol of eukaryotic cells. Recen...

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Bibliographic Details
Main Authors: Francesca Pontiroli, Olivier Dussurget, Ivan Zanoni, Matteo Urbano, Ottavio Beretta, Francesca Granucci, Paola Ricciardi-Castagnoli, Pascale Cossart, Maria Foti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912878/?tool=EBI