Mice with deficiency in Pcdh15, a gene associated with bipolar disorders, exhibit significantly elevated diurnal amplitudes of locomotion and body temperature

Mice with deficiency in Pcdh15, a gene associated with bipolar disorders, exhibit significantly elevated diurnal amplitudes of locomotion and body temperature

Abstract Genetic factors significantly affect the pathogenesis of psychiatric disorders. However, the specific pathogenic mechanisms underlying these effects are not fully understood. Recent extensive genomic studies have implicated the protocadherin-related 15 (PCDH15) gene in the onset of psychiat...

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Bibliographic Details
Main Authors: Daisuke Mori, Chihiro Inami, Ryosuke Ikeda, Masahito Sawahata, Shinji Urata, Sho T. Yamaguchi, Yohei Kobayashi, Kosuke Fujita, Yuko Arioka, Hiroki Okumura, Itaru Kushima, Akiko Kodama, Toshiaki Suzuki, Takashi Hirao, Akira Yoshimi, Akira Sobue, Takahiro Ito, Yukikiro Noda, Hiroyuki Mizoguchi, Taku Nagai, Kozo Kaibuchi, Shigeo Okabe, Koji Nishiguchi, Kazuhiko Kume, Kiyofumi Yamada, Norio Ozaki
Format: Article
Language:English
Published: Nature Publishing Group 2024-05-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-024-02952-6

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https://doi.org/10.1038/s41398-024-02952-6

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