Engineering the L-tryptophan metabolism for efficient de novo biosynthesis of tryptophol in Saccharomyces cerevisiae

Engineering the L-tryptophan metabolism for efficient de novo biosynthesis of tryptophol in Saccharomyces cerevisiae

Abstract Tryptophol (IET) is a metabolite derived from L-tryptophan that can be isolated from plants, bacteria, and fungi and has a wide range of biological activities in living systems. Despite the fact that IET biosynthesis pathways exist naturally in living organisms, industrial-scale production...

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Bibliographic Details
Main Authors: Ye Li, Jingzhen Sun, Zhenhao Fu, Yubing He, Xiaorui Chen, Shijie Wang, Lele Zhang, Jiansheng Jian, Weihua Yang, Chunli Liu, Xiuxia Liu, Yankun Yang, Zhonghu Bai
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Aromatic amino acids
Ehrlich pathway
Metabolic engineering
Saccharomyces cerevisiae
L-Tryptophan
Tryptophol
Online Access:https://doi.org/10.1186/s13068-024-02576-4

Internet

https://doi.org/10.1186/s13068-024-02576-4

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