DNMT aberration-incurred GPX4 suppression prompts osteoblast ferroptosis and osteoporosis
Abstract Osteoporosis (OP) is a common and fracture-prone skeletal disease characterized by deteriorated trabecular microstructure and pathologically involving various forms of regulated bone cell death. However, the exact role, cellular nature and regulatory mechanisms of ferroptosis in OP are not...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2024-12-01
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| Series: | Bone Research |
| Online Access: | https://doi.org/10.1038/s41413-024-00365-1 |