The Role of Renin-Angiotensin-Aldosterone System in the Heart and Lung: Focus on COVID-19

The renin-angiotensin-aldosterone system (RAAS) firstly considered as a cardiovascular circulating hormonal system, it is now accepted as a local tissue system that works synergistically or independently with the circulating one. Evidence states that tissue RAAS locally generates mediators with regu...

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Bibliographic Details
Main Authors: Annamaria Mascolo, Cristina Scavone, Concetta Rafaniello, Antonella De Angelis, Konrad Urbanek, Gabriella di Mauro, Donato Cappetta, Liberato Berrino, Francesco Rossi, Annalisa Capuano
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.667254/full