PS4DR: a multimodal workflow for identification and prioritization of drugs based on pathway signatures

Abstract Background During the last decade, there has been a surge towards computational drug repositioning owing to constantly increasing -omics data in the biomedical research field. While numerous existing methods focus on the integration of heterogeneous data to propose candidate drugs, it is st...

Full description

Bibliographic Details
Main Authors: Mohammad Asif Emon, Daniel Domingo-Fernández, Charles Tapley Hoyt, Martin Hofmann-Apitius
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-03568-5