Preclinical assessment of synergistic efficacy of MELK and CDK inhibitors in adrenocortical cancer
Abstract Background Adrenocortical cancer (ACC) is a rare and aggressive cancer with dismal 5-year survival due to a lack of effective treatments. We aimed to identify a new effective combination of drugs and investigated their synergistic efficacy in ACC preclinical models. Methods A quantitative h...
Main Authors: | Dipranjan Laha, Robert R.C. Grant, Prachi Mishra, Myriem Boufraqech, Min Shen, Ya-Qin Zhang, Matthew D. Hall, Martha Quezado, Michelly Sampaio De Melo, Jaydira Del Rivero, Martha Zeiger, Naris Nilubol |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-09-01
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Series: | Journal of Experimental & Clinical Cancer Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13046-022-02464-5 |
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