Molecular characterization of ambiguous mutations in HIV-1 polymerase gene: implications for monitoring HIV infection status and drug resistance.

Molecular characterization of ambiguous mutations in HIV-1 polymerase gene: implications for monitoring HIV infection status and drug resistance.

Detection of recent HIV infections is a prerequisite for reliable estimations of transmitted HIV drug resistance (t-HIVDR) and incidence. However, accurately identifying recent HIV infection is challenging due partially to the limitations of current serological tests. Ambiguous nucleotides are newly...

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Bibliographic Details
Main Authors: Du-Ping Zheng, Margarida Rodrigues, Ebi Bile, Duc B Nguyen, Karidia Diallo, Joshua R DeVos, John N Nkengasong, Chunfu Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3798419?pdf=render

Internet

http://europepmc.org/articles/PMC3798419?pdf=render

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