Identification of stable housekeeping genes for induced pluripotent stem cells and -derived endothelial cells for drug testing

Identification of stable housekeeping genes for induced pluripotent stem cells and -derived endothelial cells for drug testing

Abstract There are no validated housekeeping genes in induced pluripotent stem cells (iPSC) and derived endothelial iPSC (iPSC-EC). Thus a comparison of gene expression levels is less reliable, especially during drug treatments. Here, we utilized transcriptome sequencing data of iPSC and iPSC-EC wit...

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Bibliographic Details
Main Authors: Sheena L. M. Ong, Hans J. Baelde, David G. P. van IJzendoorn, Judith V. M. G. Bovée, Karoly Szuhai
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20435-w

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https://doi.org/10.1038/s41598-022-20435-w

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