Proarrhythmic changes in human cardiomyocytes during hypothermia by milrinone and isoprenaline, but not levosimendan: an experimental in vitro study

Proarrhythmic changes in human cardiomyocytes during hypothermia by milrinone and isoprenaline, but not levosimendan: an experimental in vitro study

Abstract Background Accidental hypothermia, recognized by core temperature below 35 °C, is a lethal condition with a mortality rate up to 25%. Hypothermia-induced cardiac dysfunction causing increased total peripheral resistance and reduced cardiac output contributes to the high mortality rate in th...

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Bibliographic Details
Main Authors: Anders Lund Selli, Mohammadreza Ghasemi, Taylor Watters, Francis Burton, Godfrey Smith, Erik Sveberg Dietrichs
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Subjects:
Levosimendan
Milrinone
Isoprenaline
Hypothermia
Cardiomyocytes
Electrophysiology
Online Access:https://doi.org/10.1186/s13049-023-01134-5

Internet

https://doi.org/10.1186/s13049-023-01134-5

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