Kaempferol Inhibits Hepatic Stellate Cell Activation by Regulating miR-26b-5p/Jag1 Axis and Notch Pathway

Kaempferol Inhibits Hepatic Stellate Cell Activation by Regulating miR-26b-5p/Jag1 Axis and Notch Pathway

Kaempferol, a natural flavonoid molecule, has demonstrated anti-inflammatory, antimicrobial and antioxidant activities. Recent studies have shown the beneficial effects of kaempferol on liver fibrosis. Notch pathway has been reported to be involved in the aberrant activation of hepatic stellate cell...

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Bibliographic Details
Main Authors: Guangyao Zhou, Chunxue Li, Rongrong Zhang, Yating Zhan, Lifan Lin, Zhichao Lang, Qiqi Tao, Jianjian Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
kaempferol
miR-26b-5p
JAG1
hepatic stellate cell
liver fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.881855/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.881855/full

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