Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface.

Galectin-3 induces clustering of CD147 and integrin-β1 transmembrane glycoprotein receptors on the RPE cell surface.

Proliferative vitreoretinopathy (PVR) is a blinding disease frequently occurring after retinal detachment surgery. Adhesion, migration and matrix remodeling of dedifferentiated retinal pigment epithelial (RPE) cells characterize the onset of the disease. Treatment options are still restrained and id...

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Bibliographic Details
Main Authors: Claudia S Priglinger, Christoph M Szober, Siegfried G Priglinger, Juliane Merl, Kerstin N Euler, Marcus Kernt, Gabor Gondi, Jennifer Behler, Arie Geerlof, Anselm Kampik, Marius Ueffing, Stefanie M Hauck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726584?pdf=render

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http://europepmc.org/articles/PMC3726584?pdf=render

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