A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in <i>Fasciola hepatica</i> Carboxylesterase B

A Single Nucleotide Polymorphism Translates into a Radical Amino Acid Substitution at the Ligand-Binding Site in <i>Fasciola hepatica</i> Carboxylesterase B

<i>Fasciola hepatica</i> anthelmintic resistance may be associated with the catalytic activity of xenobiotic metabolizing enzymes. The gene expression of one of these enzymes, identified as carboxylesterase B (CestB), was previously described as inducible in adult parasites under anthelm...

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Bibliographic Details
Main Authors: Estefan Miranda-Miranda, Silvana Scarcella, Enrique Reynaud, Verónica Narváez-Padilla, Gisela Neira, Roberto Mera-y-Sierra, Hugo Aguilar-Díaz, Raquel Cossio-Bayugar
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Genes
Subjects:
SNTP
carboxylesterase
amino acid substitution
<i>Fasciola hepatica</i>
anthelmintic resistance
bioinformatics
Online Access:https://www.mdpi.com/2073-4425/13/10/1899

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https://www.mdpi.com/2073-4425/13/10/1899

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