The regulatory effect of hyaluronan on human mesenchymal stem cells’ fate modulates their interaction with cancer cells in vitro

Abstract Metastatic spread of cancer cells into a pre-metastatic niche is highly dependent on a supporting microenvironment. Human bone marrow-derived mesenchymal stem cells (bmMSCs) contribute to the tumor microenvironment and promote cancer metastasis by inducing epithelial-to-mesenchymal transiti...

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Bibliografski detalji
Glavni autori: Christian Vogeley, Özer Degistirici, Sören Twarock, Jessica Wladarz, Oliver Reiners, Tobias Gorges, Jens W. Fischer, Roland Meisel, Katharina Gorges
Format: Članak
Jezik:English
Izdano: Nature Portfolio 2021-10-01
Serija:Scientific Reports
Online pristup:https://doi.org/10.1038/s41598-021-00754-0