Nardosinone Enhances Nerve Growth Factor-Induced Neurite Outgrowth in a Mitogen-Activated Protein Kinase- and Protein Kinase C-Dependent Manner in PC12D Cells

ABSTRACT: The mechanism to enhance nerve growth factor (NGF, 2 ng/ml)-induced neurite outgrowth from PC12D cells by nardosinone isolated from Nardostachys chinensis was examined. It was shown that the potentiation of the NGF-induced neurite outgrowth by nardosinone was mitogen-activated protein (MAP...

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Bibliographic Details
Main Authors: Ping Li, Tohru Yamakuni, Kimihiro Matsunaga, Shunzo Kondo, Yasushi Ohizumi
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319326246