Single-cell RNA-seq analyses inform necroptosis-associated myeloid lineages influence the immune landscape of pancreas cancer

IntroductionTumor-infiltrating myeloid cells (TIMs) are key regulators in tumor progression, but the similarity and distinction of their fundamental properties in pancreatic ductal adenocarcinoma (PDAC) remain elusive.MethodIn this study, we conducted scRNA-seq data analysis of cells from 12 primary...

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Bibliographic Details
Main Authors: Weiwei Dong, Huixia Zhao, Shanshan Xiao, Liuqing Zheng, Tongqiang Fan, Li Wang, He Zhang, Yanyan Hu, Jingwen Yang, Tao Wang, Wenhua Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1263633/full