Rolling uphill: in vivo reacquisition of pluripotency during cranial neural crest differentiation
Conrad Waddington famously used his epigenetic landscape to describe the paths a cell might take during developmental differentiation. In this analogy, the undifferentiated stem cell begins at the highest elevation and proceeds to tumble downward towards its final resting place, representing termina...
Автори: | , |
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Формат: | Стаття |
Мова: | English |
Опубліковано: |
Nature Portfolio
2021-05-01
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Серія: | Communications Biology |
Онлайн доступ: | https://doi.org/10.1038/s42003-021-02154-6 |