Rolling uphill: in vivo reacquisition of pluripotency during cranial neural crest differentiation

Conrad Waddington famously used his epigenetic landscape to describe the paths a cell might take during developmental differentiation. In this analogy, the undifferentiated stem cell begins at the highest elevation and proceeds to tumble downward towards its final resting place, representing termina...

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Бібліографічні деталі
Автори: Fanju W. Meng, Patrick J. Murphy
Формат: Стаття
Мова:English
Опубліковано: Nature Portfolio 2021-05-01
Серія:Communications Biology
Онлайн доступ:https://doi.org/10.1038/s42003-021-02154-6